Orbs of alchemy upgrade items from Normal to Rare. Items are graded as normal, magic, rare and unique items. While rare item can have up to 6 modifiers, these items are more valuable. Furthermore, orb of alchemy can be used in various vendor recipes, purchase other currency or items, and crafting items at crafting bench in your hideout.
(1) Farming orb of alchemy by slain monsters. When level your character to 2, you have a chance to acquire orb of alchemy. Kill Monsters of higher rarity will obtain a higher item level. Open more chests and strongboxes can acquire orbs of alchemy as well.
(2) Vendoring unique items to alchemy orb shards, 20 shards will combine to 1 orb of alchemy orbs automatically. In order to sustain alchemy orbs, pick up every unique item while farming Poe currency. I have farmed hundreds of orbs of alchemy using this strategy.
(3) Buy orb of alchemy from Clarissa(Act 3, The Sarn Encampment) for 1 orb of Regret.
(4) “The Alchemist” is the prophecy of an orb of alchemy.
(5) A set of 3 “The Survivalist” can exchange to 7 orbs of alchemy.
(6) Buy orb of alchemy $0.66 / 200 with 3% off coupon “AOE”.
One can farm hundreds of Orbs of Alchemy by using Alchemy Shards recipe, purchase from the vendor, Orb of Alchemy recipe, prophecy, and divination cards. Exchange PoE currency and items with other players can obtain lots of Orbs of Alchemy as well.
Alchemy Shard Recipe generally comes from items with corrupted and enchanted modifiers. More often, unique items have all had these mods and can vendor for alchemy shares with this recipe. 20 Alchemy shards combine to form an Orb of Alchemy automatically.
Generally, pick up every unique item and vendors for orbs of alchemy. I have farmed lots of alchemy with this means. The items with the following mods can also a vendor for alchemy shards as well:
|1× Alchemy Shard||
|2× Alchemy Shard (*)
2× Alteration Shard
|3× Alchemy Shard||
|4× Alchemy Shard||
|4× Alchemy Shard
7× Alteration Shard
|Orb of Alchemy||1× Orb of Regret||Act 3 (Clarissa)|
Clarissa lives in The Sarn Encampment of Act 3, sell an Orb of Alchemy for an Orb of Regret. One can purchases alchemy directly if have lots of Orbs of Regret.
|1× Orb of Alchemy||3 x Identified rare items with the same name|
|1× Orb of Alchemy||2 x Identified rare items with the same name and both 20% quality|
|1× Orb of Alchemy||normal, magic, rare (all 20% quality)|
|2× Orb of Alchemy||normal, magic, rare (all 20% quality and unidentified)|
These recipes are difficult and cost much time to collect items. I recommend using Alchemy Shards recipe, which picking up unique items for vendor orbs of alchemy.
“The Alchemist” is a prophecy, which rewarding an Orb of Alchemy. Farm “The Alchemist” by killing any “Undying Alchemist”. One can find in these areas: Act 3 – The Sewers, Act 8 – Doedre’s Cesspool (The Toxic Conduits), Map – Cells, Map – Toxic Sewer, Map – Shore (rare), Map – Channel (rare), and Olmec’s Sanctum.
A set of 3 “The Survivalist” can exchange 7 Orbs of Alchemy. One can obtain orb of alchemy by farming “The Survivalist” divination card in The Wetlands (Act 2).
These orbs are both crucial to a player when leveling up one’s character. Orb of alchemy upgrades a normal item into a rare item, while Chaos Orb reforged a rare item with new random mods. Currently, the orb of alchemy to chaos ratio is 21:10. One can exchange 21 Orbs of Alchemy to 10 Chaos Orbs through http://currency.poe.trade/.
Always, one can purchase 200 Orbs of Alchemy for $0.66 additional 3% discount with coupon “AOE”.
Orb of Chance upgrades item randomly. The item may become Magic, Rare, or even Unique. In fact, the most commonly will be resulting in a Magic item, uncommonly a Rare item. However, Orb of Alchemy upgrades normal item to Rare item with 100% guaranteed. Orb of Alchemy is more valuable. At present, 5 Orbs of Chance can exchange 2 Orbs of Alchemy.