PoE Sanctum Cheat Sheet

List of PoE Sanctum Cheat Sheet

Each room other than the miniboss room contains several Guard unique monsters, as well as one of three tasks to complete the room:

  • Find the Exit (locate the exit door)
  • Defeat all the Guards (defeat every Unique Guard)
  • Defeat the Boss (minibosses based on map bosses)
Sanctum Cheat Sheet
Room Goal Defeat all the Guards Defeat all the Guards
(Skull Arena)		 Find the Exit Find the Exit
(Traps)		 Defeat the Boss
(Miniboss)
Floor 1:
Sanctum Archives		 Chambers of Inscription Templar Annals
1 central Skull, walls		 Abandoned Library
Ice Trap		 Holy Trials
Mana Rune Squares		 Scriptorium
Crimson Archbishop
Floor 2:
Sanctum Vaults		 Derelict Caverns Battlegrounds
1 central Skull, no walls		 Decrepit Cellar
Ice Trap		 Gauntlet
Rolling Exarch Boulders		 Reliquary
Greater Wraith
Floor 3:
Sanctum Cathedral		 Unholy Lair Infernum
2 Skulls, dividing wall		 Halls of Worship Crucible
Mana Rune Squares		 Sanctum Bellum
Aureate Guardian
Floor 4:
Sanctum Necropolis		 Lost Catacombs Desecrated Crypt
1 Skull, 90 degree arc		 Undercroft Entombment
Rolling Exarch Boulders or
Mana Rune Squares + Lasers		 Mausoleum
Colossal Lithomancer

Note: most “Find the Exit” rooms have shortcuts that require movement skills.

Buy PoE Currency Cheap

Room Reward Types

Note: All room types other than boss rooms can become Afflicted. Afflicted rooms are indicated by a purple border and cause the character to gain an Affliction on entry.

Item Reward Room

When players are offered rewards, they have three options:

  • Recieve #x <item1> now
  • Recieve #x <item2> at end of the Floor (“at end of the next Floor” if on room 8)
  • Recieve #x <item3> on completing the Sanctum

The quantity and/or types of items improve based on the area level of the zone and how long you defer the reward, at the cost of risking the reward entirely if the player fails the run. Item chests have a 5 Aureus fee.

Treasure Reward Room

Contains chests of Aureus; comes in 2 types: Minor Treasure Reward (2 chests) or Major Treasure Reward (5 chests).

Path of Exile Guides & Tips