Chambers of Inscription -- Path of Exile

A Sanctum run contains 4 floors, each containing 8 rooms. The 8th room of each floor always contains a Boss. Players can choose to engage in a room every time they encounter the portal to the Sanctum in an area or map, or defer up to 8 rooms (1 floor) to be run consecutively at a later time. Crashing during a Sanctum room will reset progress for that room and will resume the same area on your next map. Aureus and rewards are only locked in upon successful completion of a room. Each Sanctum run is independent between characters on the same account.

Chambers of Inscription Sanctum Room

Name Icon Floor Contains
Chambers of Inscription Sanctum Archives

All room types other than boss rooms can become Afflicted. Afflicted rooms are indicated by a purple border and cause the character to gain an Affliction on entry.

Each room contains several Guard unique monsters, as well as one of three tasks to complete the room:

  • Find the Exit (locate the exit door)
  • Defeat all the Guards (defeat every unique Guard)
  • Survive (avoid the traps)
  • Defeat the Boss (minibosses based on map bosses)

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Sure, here's what I found about the Chambers of Inscription in The Forbidden Sanctum:

Chambers of Inscription is a common room type found on the first floor of The Forbidden Sanctum, an endgame Delve mechanic in Path of Exile. It's primarily a combat encounter room, testing your abilities against Sanctum enemies.

Here's what you can expect:

  • Layout: The Chambers of Inscription is a moderately sized room with a central platform and two elevated walkways flanking it.
  • Enemies: The room is typically occupied by two groups of Sanctum Guards, one on each walkway. These are moderately tough humanoid enemies wielding spears and shields. There's a chance for a third elite guard to spawn in the center platform, adding extra challenge.
  • Untargetable Dogs: Additionally, there are two untargetable dog-like phantoms patrolling the room perimeter. These phantoms deal no damage but can activate traps and trigger certain room mechanics. To target them, you need to walk through them, making for an interesting tactical element.
  • Pressure Plates: Scattered throughout the room are pressure plates. Walking on them activates traps that shoot arrows from the walls. Careful positioning and awareness are key to avoiding these.

Tips:

  • Focus on the Sanctum Guards first: They are the main threat in the room and can quickly overwhelm you if not dealt with efficiently.
  • Lure the guards to the center platform: This gives you more space to maneuver and avoid pressure plate traps.
  • Use the untargetable dogs strategically: You can lure them onto pressure plates to activate traps against the guards.
  • Be mindful of your surroundings: Keep an eye out for trap indicators and adjust your positioning accordingly.

Overall, the Chambers of Inscription is a straightforward combat encounter that tests your basic combat skills and awareness. By approaching it strategically and utilizing the room mechanics to your advantage, you can overcome the challenges it presents.


List of Sanctum Rooms

Name Icon Floor Contains
Abandoned Library Sanctum Archives
Templar Annals Sanctum Archives
Chambers of Inscription Sanctum Archives
Holy Trials Sanctum Archives
Scriptorium Sanctum Archives
Candlelit Chapel Sanctum Archives
Merchant Sanctum Archives Contains Merchant
Accursed Pact Sanctum Archives Contains Accursed Pact
Fountain Sanctum Archives Contains Fountain
Afflicted Fountain Sanctum Archives Contains Afflicted Fountain
Benevolent Fountain Sanctum Archives Contains Benevolent Fountain
Radiant Fountain Sanctum Archives Contains Radiant Fountain
Offer Sanctum Archives Offers Items on Completion
Major Treasure Sanctum Archives Contains Major Treasure Reward
Minor Treasure Sanctum Archives Contains Minor Treasure Reward
Candlelit Chapel Sanctum Archives Contains Varakath, the Waxen
Battleground Sanctum Vaults
Decrepit Cellar Sanctum Vaults
Derelict Caverns Sanctum Vaults
Gauntlet Sanctum Vaults
Reliquary Sanctum Vaults
Experimentation Chamber Sanctum Vaults
Merchant Sanctum Vaults Contains Merchant
Accursed Pact Sanctum Vaults Contains Accursed Pact
Fountain Sanctum Vaults Contains Fountain
Afflicted Fountain Sanctum Vaults Contains Afflicted Fountain
Benevolent Fountain Sanctum Vaults Contains Benevolent Fountain
Radiant Fountain Sanctum Vaults Contains Radiant Fountain
Offer Sanctum Vaults Offers Items on Completion
Major Treasure Sanctum Vaults Contains Major Treasure Reward
Minor Treasure Sanctum Vaults Contains Minor Treasure Reward
Candlelit Chapel Sanctum Vaults Contains Braom and Uzar, the Experiments
Halls of Worship Sanctum Cathedral
Unholy Lair Sanctum Cathedral
Infernum Sanctum Cathedral
Crucible Sanctum Cathedral
Sanctum Bellum Sanctum Cathedral
Hall of Mirrors Sanctum Cathedral
Merchant Sanctum Cathedral Contains Merchant
Accursed Pact Sanctum Cathedral Contains Accursed Pact
Offer Sanctum Cathedral Offers Items on Completion
Fountain Sanctum Cathedral Contains Fountain
Afflicted Fountain Sanctum Cathedral Contains Afflicted Fountain
Benevolent Fountain Sanctum Cathedral Contains Benevolent Fountain
Radiant Fountain Sanctum Cathedral Contains Radiant Fountain
Major Treasure Sanctum Cathedral Contains Major Treasure Reward
Minor Treasure Sanctum Cathedral Contains Minor Treasure Reward
Candlelit Chapel Sanctum Cathedral Contains Xenathar, Templar Reaper
Lost Catacombs Sanctum Necropolis
Desecrated Crypts Sanctum Necropolis
Undercroft Sanctum Necropolis
Entombment Sanctum Necropolis
Mausoleum Sanctum Necropolis
Sanctum Sanctorum Sanctum Necropolis
Fountain Sanctum Necropolis Contains Fountain
Afflicted Fountain Sanctum Necropolis Contains Afflicted Fountain
Benevolent Fountain Sanctum Necropolis Contains Benevolent Fountain
Radiant Fountain Sanctum Necropolis Contains Radiant Fountain
Merchant Sanctum Necropolis Contains Merchant
Accursed Pact Sanctum Necropolis Contains Accursed Pact
Offer Sanctum Necropolis Offers Items on Completion
Major Treasure Sanctum Necropolis Contains Major Treasure Reward
Minor Treasure Sanctum Necropolis Contains Minor Treasure Reward
Candlelit Chapel Sanctum Necropolis Contains Lycia, Unholy Heretic