Complete Forbidden Sanctum Floors that are area level 81 or higher x50 PoE

A Sanctum run contains 4 floors, each containing 8 rooms. The 8th room of each floor always contains a Boss. Players can choose to engage in a room every time they encounter the portal to the Sanctum in an area or map, or defer up to 8 rooms (1 floor) to be run consecutively at a later time. Crashing during a Sanctum room will reset progress for that room and will resume the same area on your next map. Aureus and rewards are only locked in upon successful completion of a room. Each Sanctum run is independent between characters on the same account.

Room Layouts

Sanctum Layout
Header text Kill all the Guards Kill all the Guards
(Skull Arena)
Find the Exit Find the Exit (Traps) Defeat the Boss (Miniboss)
Floor 1:
Sanctum Archives
Chambers of Inscription Templar Annals
1 central Skull, walls
Abandoned Library Holy Trials
Mana Rune Squares
Scriptorium
Floor 2:
Sanctum Vaults
Derelict Caverns Battlegrounds
1 central Skull, no walls
Decrepit Cellar Gauntlet Reliquary
Floor 3:
Sanctum Cathedral
Unholy Lair Infernum
2 Skulls, dividing wall
Halls of Worship Crucible Sanctum Bellum
Floor 4:
Sanctum Necropolis
Lost Catacombs Desecrated Crypt
1 Skull, 90 degree arc
Undercroft Entombment
Rolling Boulders
Mausoleum

Note: most “Find the Exit” rooms have shortcuts that require movement skills.

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Floor Bosses

Sanctum Bosses
Boss name Boss room name Based on:
Varakath, the Waxen Sanctum Archives: Candlelit Chapel Candlemass (POE2); also uses Blazing Salvo and a fire breath attack
Braom, the First Experiment
Uzar, the Second Experiment
Sanctum Vaults: Experimentation Chamber Slow moving statues that use slams. Braom can use a multidirectional Glacial Cascade, or Sunder while walking. Uzar can also create a homing Blood Orb leaving Enervating Ground. The bosses enrage when the other dies.
Xenathar, Templar Reaper Sanctum Cathedral: Hall of Mirrors Vorana, Last to Fall; also uses wall-bouncing lasers, Divine Flare, and slow-moving Innocence projectile nova.
Lycia, Unholy Heretic Sanctum Necropolis: Sanctum Sanctorum Phase 1: Attacks with sword swings and lunges, can summon Igneous Gargoyle adds and spawns a ring of DOT ground effect that drains Resolve.
Lycia, Herald of the Scourge The Beyond Phase 2: Fires rotating lasers, an outward moving maze of sparks, and spinning staves. Does not damage resolve.
  • Bosses drop a large quantity of Aureus and have a chance to drop Templar relics (or Sanctified Relics at area levels >75).
  • Killing each boss for the first time unlocks several tiles in the Relic Altar.
  • Boss rooms contain a chest for any accumulated Item Rewards for the floor, as well as two additional Item Reward chests.
  • After defeating Lycia’s first phase, the player can either directly exit to the reward chest via the staircase (and therefore unable to enter The Beyond), or enter The Beyond to challenge her second phase. Dying during the second phase will end the run and prevent looting of the reward chest.
  • Lycia’s second form is only encounterable in an area of level 80 (T13+ maps); she will only taunt the player after being killed in lower areas.
  • Lycia’s second form does not interact with Resolve mechanics; however, it is still possible to fail from the Resolve mechanic if the player has an Affliction that removes Resolve on flask use.

Lycia, Herald of the Scourge in “The Beyond” will always drop a Sanctified Relic, as well as:

  • Sandstorm Visage
  • The Balance of Terror
  • Eternal Damnation
  • The Winds of Fate

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