The Agnostic is a keystone passive skill that removes your energy shield and drains mana per second to recover your life while you are not at full life.
From PoE 3.11.0, it was added to the main skill tree.
The Agnostic Keystone
This keystone will conquer any keystones within the radius of a Militant Faith jewel with modifier Carved to glorify (2000-10000) new faithful converted by High Templar Venarius.
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GGG has added new keystones to the Marauder-Duelist section of the tree. These allow investment in slow Impale attacks, mitigating big hits with Armour, and making Warcries more accessible to non-Warcry-invested builds. Each of these allows you to improve some weakness that certain strength-based characters, especially two handed melee characters, could have.