Culling Strike is a property that causes hits to kill enemies left with 10% of maximum life or less.
A hit with culling strike will kill an enemy if it is still alive with 10% of maximum life or less after the hit. This occurs instantly; there is no delay between the enemy taking damage from the hit and being killed by culling strike.
Culling strike does not trigger when an enemy is reduced to zero life outright by the damage inflicted by a hit. This is relevant for effects that care about overkill damage, such as Herald of Ash.
Since culling strike is a property of hits, it is not applicable to damage over time.
Vorana’s Preparation is a unique Iron Flask. Requires Level 40.