The easiest solution I found is to limit Processor power.
Make sure your computer meets the minimum hardware specs.
Restart your computer.
This can sometimes fix problems, and is simple to try.
Exclude Path of Exile from anti-virus real-time scanning (including Windows Defender).
Real-time scanning can have a significant impact on game performance on some systems.
Ensure your Path of Exile client is installed on an SSD.
While an SSD is only recommended, it is strongly recommended as it should improve loading times and reduce stuttering and graphical pop-in.
Ensure your drivers are up to date.
Modern operating systems are generally pretty good at this on their own, but it may still help to at least get the latest graphics drivers directly from your GPU manufacturer’s website.
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Ensure your OS is up to date.
If your OS is not up to date you may be missing important performance fixes.
If none of the above steps have helped, you may need to consult a qualified computer technician to check for hardware problems.