| Sanguimancy | Notable | Ascendancy Name: Warlock - Skills Cost Life instead of Mana
- Skills Reserve Life instead of Mana
- Removes all Mana
- 50% increased Life Reservation Efficiency of Skills
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| Crimson Power | Notable | Ascendancy Name: Warlock - Removes all Energy Shield
- Gain Maximum Life instead of Maximum Energy Shield from Equipped Armour Items
- -6 Maximum Life per Level
Reminder Text: - (Characters inherently gain +12 Life per Level)
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| Cannibalised Faith | Notable | Ascendancy Name: Warlock - Spells you cast yourself gain Added Physical Damage equal to 75% of Life Cost, if Life Cost is not higher than the maximum you could spend
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| Foul Pact | Notable | Ascendancy Name: Warlock - Enemies Pacified by you take 20% increased Damage
- Minions affected by Affliction have Onslaught
- Phantasms from Penance Mark have a 50% chance to grant a Vaal Soul when Killed
- Phantasms from Penance Mark grant 50% increased Flask Charges
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| Blood Hunt | Notable | Ascendancy Name: Warlock - Grants Level 20 Ravenous Skill
- Enemies display their Monster Category
Reminder Text: - (Ravenous consumes a targeted corpse, granting you a buff that causes you to deal more damage to, and take less damage from, enemies of the same Monster Category as the corpse)
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Wild Wisps found | Normal | Ascendancy Name: Warlock - 10% increased Quantity of Wild Wisps found in the Viridian Wildwood
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| Soul Splitting | Notable | Ascendancy Name: Warlock - Grants Level 20 Summon Dark Effigy Skill
Reminder Text: - (Creates a Dark Effigy tethered to you. Damage you take from enemy hits is taken from the Effigy's life before you, and damage the Effigy takes from enemy hits is taken from your life before it, at doubled value. The Effigy is destroyed if you get too far away from it)
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