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Mechanics
Enemies you Kill during Effect have a #% chance to Explode, dealing a tenth of their maximum Life as Damage of a Random Element will choose randomly between Fire, Cold, or Lightning Damage.
Scaling flask effect will scale the chance for enemies to explode.
The damage is best scaled through sources of Elemental Damage, Elemental penetration, or Elemental damage gained as extra Chaos Damage:
Crystallised Omniscience
Doryani's Catalyst
Atziri's Promise
Incandescent Heart
The Eternity Shroud
Weapons with #% increased Spell Damage; Gain 5% of Non-Chaos Damage as extra Chaos Damage incursion mod or Gain #% of Elemental Damage as Extra Chaos Damage Shaper mod.
Item acquisition
Oriath's End has restrictions on where or how it can drop. It cannot be chanced.
Drops from Uber Sirus.
Ruthless mode
Utility Flasks cannot gain charges while active in Ruthless mode. This flask also has a flask duration of 5.50 seconds instead.
Design attribution
Progenesis was created in collaboration with Steelmage as a reward for taking a prize place in the 3.18 boss kill event.