Essence of Delirium upgrades a normal item to rare or reforges a rare item, guaranteeing one property:
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PoE 3.20: Essences of Delirium now provide 6-7% chance to Block Spell Damage for Amulets (previously "Hexes you inflict have +10 to maximum Doom).
Essences have been numerically rebalanced, and are in general stronger than they were before.
Screaming Essences can now be used to reroll rare items, in addition to their capability to upgrade items to rare.
The four corrupted Essences(Essence of Hysteria, Essence of Insanity, Essence of Horror, and Essence of Delirium) have had some of their less-useful outcomes improved or replaced.
Now, the only way to get the powerful upgrade-only top-tier essences is through Remnants of Corruption, which come from Essence content.
Essence of Delirium can only be obtained by using a Remnant of Corruption on a group of monsters trapped by an Essence of Scorn, Envy, Misery or Dread of any level (the purple map-only essences).