Location: The Fissure of Malice can be found in the Frostbite Trails, in the southwestern area of The Pallide Glade in the Fracture Peaks region.

The Fissure of Malice can be found in the Fractured Peaks region in Diablo 4, specifically in the southwestern area of the Pallide Glade.
For the quickest access to this Malignant Tunnel, start at the waypoint in Nostrava and exit from the west side of the town. Then, travel south. It will only be a short journey.
To access the Outgrowth at the end of the Malignant Tunnel, you will need either a Devious Malignant Invoker or a Wrathful Malignant Invoker.
Invoker Needed: Devious Malignant Invoker
Objectives:
Normal Enemies:
Elite Enemies: