Io Rune — Diablo 2 Resurrected

1. D2R Io Rune

Name Weapon Armor/Helms/Shields Level
Io Rune Io Rune +10 To Vitality +10 To Vitality 35

2. Io Rune Recipe

Outcome Horadric Cube Recipe
1x Io Rune Io Rune
1x Lum Rune Lum Rune

Cheap Diablo II: Resurrected Items

3. Runewords with Io Rune

Runewords Allowed Items Runewords Recipes Level Complete Stats
Pride 4 Socket Polearms Cham Rune Cham Rune + Sur Rune Sur Rune + Io Rune Io Rune + Lo Rune Lo Rune 67 25% Chance To Cast Level 17 Fire Wall When Struck
Level 16-20 Concentration Aura When Equipped
260-300% Bonus To Attack Rating
+1-99% Damage To Demons (Based on Character Level)
Adds 50-280 Lightning Damage
20% Deadly Strike
Hit Blinds Target
Freezes Target +3
+10 To Vitality
Replenish Life +8
1.875-185.625% Extra Gold From Monsters (Based on Character Level)
White 2 Socket Wand Dol Rune Dol Rune + Io Rune Io Rune 35 Hit Causes Monster To Flee 25%
+10 To Vitality
+3 To Poison And Bone Spells (Necromancer Only)
+3 To Bone Armor (Necromancer Only)
+2 To Bone Spear (Necromancer Only)
+4 To Skeleton Mastery (Necromancer Only)
Magic Damage Reduced By 4
20% Faster Cast Rate
+13 To Mana
Dream 3 Socket Helms/
3 Socket Shields		 Io Rune Io Rune + Jah Rune Jah Rune + Pul Rune Pul Rune 65 10% Chance To Cast Level 15 Confuse When Struck
Level 15 Holy Shock Aura When Equipped
+20-30% Faster Hit Recovery
+30% Enhanced Defense
+150-220 Defense
+10 To Vitality
Increase Maximum Life 5% (Helms Only)
+50 To Life (Shields Only)
+0.625-61.875 To Mana (Based On Character Level)
All Resistances +5-20
12-25% Better Chance of Getting Magic Items
Delirium 3 Socket Helm Lem Rune Lem Rune + Ist Rune Ist Rune + Io Rune Io Rune 51 1% Chance To Cast Level 50 Delirium (morph) When Struck
6% Chance To Cast Level 14 Mind Blast When Struck
14% Chance To Cast Level 13 Terror When Struck
11% Chance To Cast Level 18 Confuse On Striking
+2 To All Skills
+261 Defense
+10 To Vitality
50% Extra Gold From Monsters
25% Better Chance of Getting Magic Items
Level 17 Attract (60 Charges)
Memory 4 Socket Staves Lum Rune Lum Rune + Io Rune Io Rune + Sol Rune Sol Rune + Eth Rune Eth Rune 37 +3 to Sorceress Skill Levels
33% Faster Cast Rate
Increase Maximum Mana 20%
+3 Energy Shield (Sorceress Only)
+2 Static Field (Sorceress Only)
+10 To Energy
+10 To Vitality
+9 To Minimum Damage
-25% Target Defense
Magic Damage Reduced By 7
+50% Enhanced Defense
Black 3 Socket Clubs/
3 Socket Hammers/
3 Socket Maces		 Thul Rune Thul Rune + Io Rune Io Rune + Nef Rune Nef Rune 35 +120% Enhanced Damage
40% Chance Of Crushing Blow
+200 To Attack Rating
Adds 3-14 Cold Damage - Cold Duration 3 Seconds
+10 To Vitality
15% Increased Attack Speed
Knockback
Magic Damage Reduced By 2
Level 4 Corpse Explosion (12 Charges)

4. Io Rune Farming

Io Rune Io Rune is a rare rune. Where to find:

  • Countess Difficulty: Nightmare/Hell.
  • Hellforge Quest Reward Lvl: Nightmare/Hell.
  • Io Runes also have a low chance to drop from Good treasure chests. Minimum Treasure Chest Class: Act 1 (Nightmare) Good treasure class and above.

Guides & Tips