Profane Chemistry

Profane Chemistry is a notable passive skill.

  • 6% increased maximum Life
  • 30% increased Life Recovery from Flasks
  • Life Flasks gain 1 Charge every 3 seconds
Profane Chemistry PoE

PoE 3.15 Changes

The Profane Chemistry Notable no longer grants “Flasks applied to you have 8% increased Effect”. It now grants “Life Flasks gain 1 Charge every 3 seconds”.

Available by anointing Amulets

Anoint oil recipe: Verdant Oil Verdant Oil + Black Oil Black Oil + Silver Oil Silver Oil

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