PoE Tinctures 3.25 — List of Path of Exile Tinctures

In the latest 3.25 update of Path of Exile (PoE), a new mechanic known as Tinctures has been introduced into the core game. Tinctures bring an innovative twist to gameplay, offering players a new form of temporary buff that enhances melee attacks but comes with a unique drawback: Mana Burn.

  • Tinctures have been added to the core game, with adjusted mechanics. You can place a Tincture in one of your Belt slots instead of a Flask. While a Tincture is active it grants you a powerful buff to your melee attacks, but inflicts Mana Burn on you, draining your mana at an increasing rate the longer the Tincture has been active. The Tincture can be manually deactivated, or will automatically deactivate when you run out of mana.
  • You can inherently only have one Tincture active at a time. Tinctures also have a cooldown, so once you have deactivated one, no Tincture can be activated for a time. Like Flasks, Tinctures can be Magic or Unique but not Rare.
  • NPCs in towns may now have Tinctures available to purchase.
  • Added a new Bloodsoaked Blade Keystone Passive Skill to the south-east of the Duelist’s starting location. Bloodsoaked Blade causes Tinctures to inflict Weeping Wounds instead of Mana Burn, draining your life instead of your mana.
  • A new Nature’s Concoction cluster has been added to the south of the Ranger’s starting location. Nature’s Concoction provides “Flasks adjacent to applied Tincture gain 2 charges when you Hit an Enemy with a Weapon, no more than once every second”.
  • A new Perfected Formula cluster has been added to the south-east of the Ranger’s starting location. Perfected Formula provides 15% chance for Tincture to not inflict Mana Burn and causes Tinctures applied to you to have 10% reduced Mana Burn rate.
  • A new Practised Reapplication cluster has been added to the east of the Ranger’s starting location. Practised Reapplication provides 25% increased Tincture Cooldown Recovery Rate.
  • A new Colloidal Mixture cluster has been added to the north-east of the Ranger’s starting location. Colloidal Mixture causes Tinctures applied to you to have 15% increased Effect, and 15% increased Effect if you’ve used a Life Flask Recently.
  • A new Burst of Energy cluster has been added to the north-east of the Ranger’s starting location. Burst of Energy causes you to Recover 15% of Mana when you activate a Tincture.
  • Added a set of Tincture Passive Masteries:
  • The first 6 stacks of Mana Burn applied to you have no effect
  • 30% increased Evasion Rating while you have an active Tincture
  • 1% increased Flask Charges gained per Mana Burn on you
  • Flasks adjacent to applied Tincture have 10% increased Effect when used if you’ve Hit an enemy with a Weapon Recently
  • Tinctures deactivate when you have 12 or more Mana Burn

1. Prismatic Tincture

Prismatic Tincture ia a tincture base type. Inflicts Mana Burn every 0.70 Seconds. 8 Second Cooldown when Deactivated.

Requires Level 18.

  • (70–100)% increased Elemental Damage with Melee Weapons

Unique Item: Sap of the Seasons

Sap of the Seasons is a unique Prismatic Tincture.

2. Rosethorn Tincture

Rosethorn Tincture ia a tincture base type. Inflicts Mana Burn every 0.70 Seconds. 8 Second Cooldown when Deactivated.

Requires Level 18.

  • (100–150)% increased Critical Strike Chance with Melee Weapons

There are currently no unique items for this base item type.

3. Ironwood Tincture

Ironwood Tincture ia a tincture base type. Inflicts Mana Burn every 0.90 Seconds. 10 Second Cooldown when Deactivated.

Requires Level 18.

  • 40% reduced Enemy Stun Threshold with Melee Weapons
  • (15–25)% increased Stun Duration with Melee Weapons

Unique Item: Mightblood Ire

Mightblood Ire is a unique Ironwood Tincture.

4. Ashbark Tincture

Ashbark Tincture ia a tincture base type. Inflicts Mana Burn every 0.60 Seconds. 7 Second Cooldown when Deactivated.

Requires Level 32.

  • 25% chance to Ignite with Melee Weapons
  • (60–90)% increased Damage with Ignite from Melee Weapons

Unique Item: Wildfire Phloem

Wildfire Phloem is a unique Ashbark Tincture.

5. Borealwood Tincture

Borealwood Tincture ia a tincture base type. Inflicts Mana Burn every 0.60 Seconds. 7 Second Cooldown when Deactivated.

Requires Level 32.

  • 25% chance to Freeze with Melee Weapons
  • (25–35)% increased Effect of Chill from Melee Weapons

There are currently no unique items for this base item type.

6. Fulgurite Tincture

Fulgurite Tincture ia a tincture base type. Inflicts Mana Burn every 0.60 Seconds. 7 Second Cooldown when Deactivated.

Requires Level 32.

  • 25% chance to Shock with Melee Weapons
  • (25–35)% increased Effect of Shock from Melee Weapons

There are currently no unique items for this base item type.

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7. Poisonberry Tincture

Poisonberry Tincture ia a tincture base type. Inflicts Mana Burn every 0.70 Seconds. 6 Second Cooldown when Deactivated.

Requires Level 45.

  • 20% chance to Poison with Melee Weapons
  • (60–90)% increased Damage with Poison from Melee Weapons

There are currently no unique items for this base item type.

8. Blood Sap Tincture

Blood Sap Tincture ia a tincture base type. Inflicts Mana Burn every 0.70 Seconds. 6 Second Cooldown when Deactivated.

Requires Level 45.

  • 20% chance to cause Bleeding with Melee Weapons
  • (60–90)% increased Damage with Bleeding from Melee Weapons

There are currently no unique items for this base item type.

9. Oakbranch Tincture

Oakbranch Tincture ia a tincture base type. Inflicts Mana Burn every 0.50 Seconds. 8 Second Cooldown when Deactivated.

Requires Level 60.

  • Gain 3 Rage on Melee Weapon Hit

Unique Item: The Battle Within

The Battle Within is a unique Oakbranch Tincture.

10. Sporebloom Tincture

Sporebloom Tincture ia a tincture base type. Inflicts Mana Burn every 0.90 Seconds. 8 Second Cooldown when Deactivated.

Requires Level 52.

  • 25% chance to Blind Enemies on Hit with Melee Weapons
  • (25–35)% increased Effect of Blind from Melee Weapons

Unique Item: Grasping Nightshade

Grasping Nightshade is a unique Sporebloom Tincture.

Conclusion

The addition of Tinctures in PoE’s 3.25 update introduces a fresh layer of strategy, particularly for melee-focused builds. By balancing the powerful buffs against the drawback of Mana Burn, players are encouraged to think critically about when and how to use Tinctures effectively. With new passive skill clusters and masteries to support this mechanic, Tinctures offer exciting new possibilities for customizing your character’s playstyle in Path of Exile.

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