PoE Mana Burn Guide

Tinctures in Path of Exile are items that enhance melee weapons with special bonuses but cause Mana Burn, leading to mana loss over time. These can be equipped in a flask slot and activated for powerful effects.

(Mana Burn causes you to lose 1% of your maximum Mana per stack per second)

Mechanics

Activation: Upon use, tinctures grant effects and apply Mana Burn, causing 1% mana loss per stack per second.

Deactivation: Tinctures deactivate when reaching 0 mana or manually, triggering a cooldown for all tinctures.

Effect Application: Applies only to melee weapon attacks, including proxies like Blade Trap or ballistas. Does not work with unarmed skills, shields, minions, spells, wands, or bows unless specific passive skills are allocated.

Limitations: Only one tincture can be active at a time by default. The number can be increased with specific passives like Experienced Herbalist (Warden), Warden (Ascendant), and The Living Blade.

Additional Information

Types: Tinctures can be normal, magic, or unique; no rare tinctures exist.
Quality: Glassblower’s Bauble increases tincture effect by 1% per quality.
Usage: Can be used in the fifth flask slot with Micro-Distillery Belt without downsides.

Tinctures provide strategic advantages in combat, but managing Mana Burn is crucial for maintaining their benefits.

Tincture Mastery

30% increased Evasion Rating while you have an active Tincture
1% increased Flask Charges gained per Mana Burn on you
Flasks adjacent to applied Tincture have 10% increased Effect when
used if you’ve Hit an enemy with a Weapon Recently
Tinctures deactivate when you have 12 or more Mana Burn
The first 6 Mana Burn applied to you have no effect

Bloodsoaked Blade Keystone

Tinctures inflict Weeping Wounds instead of Mana Burn
Effects that interact with Mana Burn interact with Weeping Wounds instead

Enduring Suffusion warden skill

Tincture Effects Linger on you for 0.5 seconds per Mana Burn on you when the Tincture was deactivated, up to a maximum of 6 seconds
Tinctures applied to you have 30% less Mana Burn rate

Anoitable passive skills: Legacy of the Wilds

Tinctures have 40% increased effect while at or above 10 stacks of Mana Burn

Passive skills: Slower Mana Burn

Tinctures applied to you have 5% reduced Mana Burn rate

Passive skills: Perfected Formula

Tinctures applied to you have 10% reduced Mana Burn rate
15% chance for Tinctures to not inflict Mana Burn

Unique Item: The Living Blade

10% chance to remove 1 Mana Burn on Kill

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