Defeat a Delirium Boss while it has at least 50 Empowerment in an area of level 80 or higher

1. At least 50 Empowerment

Apex Sentinel empowers rare or unique enemies but have a very strong effect.

Empowerment increases the damage and damage reduction of an enemy as well as increasing experience and item yield when killed.

Search from Path of Exile Trade.

• Empowerment(Sentinel Filters): Min 50

2. An area of level 80 or higher

Search Maps from Path of Exile Trade.

• Area Level(Map Filters): Min 80

3. How to spawn PoE Delirium Boss

• Simulacrum

Simulacrum is a map fragment. Using a Simulacrum will open 6 portals to Lunacy’s Watch, The Bridge Enraptured, The Syndrome Encampment, Hysteriagate or Oriath Delusion. In these areas, you will fight delirium boss.

How to get Simulacrum

• Combine 300 Simulacrum Splinter to create a Simulacrum.
• The price of Simulacrum is about an Exalted Orb.

Fight Final Delirium Boss Strategy

The arena is based on one of the town zones, which include Lioneye’s Watch (Act 6), The Bridge Encampment (Act 7), The Sarn Encampment (Act 8), Highgate (Act 4/9), or Oriath Docks (Act 10).

There are a total of 20 waves of enemies to defeat. Interacting with the Strangely Familiar Entity will summon the wave. Each wave increases the difficulty and rewards. Higher waves add additional monster modifiers and increases the level of Delirium. Once the entire wave of enemies is cleared, it will drop all the loot listed. A Stash is available in the zone, allowing you to transfer items between waves. Starting a new wave will destroy all items on the ground.

The Delirium bosses : Omniphobia, Fear Manifest can start spawning at wave 10 and is guaranteed to spawn at wave 15 if he doesn’t spawn before, while Kosis, The Revelation can start spawning at wave 15 and is guaranteed to spawn at wave 20 if he doesn’t spawn before. Delirium Bosses have increased chance to spawn starting at wave 18 and can spawn several times per Simulacrum.

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4. Defeat Empowered Encounters

Defeat each of the following encounters while they are Empowered by a Sentinel.

• Defeat a Map Boss while it has at least 50 Empowerment in an area of level 80 or higher
• Defeat a Delirium Boss while it has at least 50 Empowerment in an area of level 80 or higher
• Defeat a Breach Boss in its domain while it has at least 50 Empowerment in an area of level 80 or higher
• Defeat a Metamorph while it has at least 50 Empowerment in an area of level 80 or higher